S12 E1: Adrian Grenier; Niecy Nash; guest co-host Chelsea Handler

S12 E2: Nastia Liukin; Meghan McCain; Judge Judy Sheindlin

S12 E3: Jamie Lee Curtis, Natalie Cole

S12 E4: Jessica Simpson; Tyler Perry

S12 E5: John McCain and Cindy Hensley McCain

S12 E6: Kim Goldman and Fred Goldman

S12 E7: Tom Bergeron, Michelle Rodriguez, a 1980s fashion show

S12 E8: Charlize Theron; Solange Knowles

S12 E9: Jason Biggs; Dave Stewart

S12 E10: David Schwimmer; Josh Lucas; Leighton Meester

S12 E11: Bill Clinton

S12 E12: Aaron Eckhart, Robert Wagner

S12 E13: Alec Baldwin

S12 E14: Chandra Wilson, Emmy look-alikes

S12 E15: Julianne Moore; Candace Bushnell

S12 E16: Jennifer Hudson; Selena Gomez; Lisa Ling

S12 E17: Bill Maher; Kevin Farley, Robert Davi , Dr. Drew Pinsky

S12 E18: Peter Krause; Diahann Carroll, Miss Piggy

S12 E19: Greg Kinnear

S12 E20: Anne Hathaway; Troy Dunn

S12 E21: Felicity Huffman

S12 E22: Gretchen Mol; Sarah Silverman

S12 E23: Dr. Susan Love, Robin Roberts

S12 E24: Angela Bassett

S12 E25: Maggie Gyllenhaal, Phil Lempert, Tristan Rogers

S12 E26: T.I.

S12 E27: Jim Cramer; Paula Deen; Gabi Wilson

S12 E28: Tony Curtis; David Alan Grier

S12 E29: Ashley Hamilton; George Hamilton

S12 E30: Richard Lewis

S12 E31: • • • • • • • • • "A Day Of Hot Topics"

S12 E32: John Lithgow; Eve

S12 E33: Bill O'Reilly

S12 E34: Debra Messing

S12 E35: Kristin Scott Thomas; Sheryl Underwood

S12 E36: Aretha Franklin

S12 E37: Duffy; Bridget Regan; Richard Dreyfuss

S12 E38: Blair Underwood; Natalie Zea; Pink

S12 E39: Jeremy Piven; Michael Phelps

S12 E40: Halloween

S12 E44: Roger Moore

S12 E45: Ricky Gervais; Mario Cantone; Steve Harvey

S12 E46: • • • • • • • • • • "A Day Of Hot Topics"

S12 E48: Alicia Keys; Amy Brenneman

S12 E53: Season 12, Episode 315

S12 E54: Season 12, Episode 316

S12 E55: Season 12, Episode 317

S12 E56: Season 12, Episode 318

S12 E57: Season 12, Episode 319

S12 E59: Season 12, Episode 321

S12 E60: Season 12, Episode 322

S12 E75: Season 12, Episode 337

S12 E77: Season 12, Episode 339

S12 E78: Season 12, Episode 340

S12 E79: Season 12, Episode 341

S12 E80: Season 12, Episode 342

S12 E81: Season 12, Episode 343

S12 E82: Season 12, Episode 344

S12 E83: Season 12, Episode 345

S12 E84: Season 12, Episode 346

S12 E85: Season 12, Episode 347

S12 E86: Season 12, Episode 348

S12 E87: Season 12, Episode 349

S12 E88: Season 12, Episode 350

S12 E89: Season 12, Episode 351

S12 E90: Season 12, Episode 352

S12 E91: Season 12, Episode 353

S12 E92: Season 12, Episode 354

S12 E93: Season 12, Episode 355

S12 E94: Season 12, Episode 356

S12 E95: Season 12, Episode 357

S12 E96: Season 12, Episode 358

S12 E97: Season 12, Episode 359

S12 E98: Season 12, Episode 360

S12 E99: Season 12, Episode 361

S12 E100: Season 12, Episode 362

S12 E101: Gov. Rod Blagojevich

S12 E102: Liza Minnelli, Padma Lakshmi

S12 E103: Liam Neeson, Jason O'Mara

S12 E104: Dr. Condoleezza Rice

S12 E105: Julianne Moore, Whitney Port, Peter Cincotti

S12 E106: A day of Hot Topics

S12 E107: Paula Deen, Dev Patel

S12 E108: Jane Seymour, Amy Dickinson, Richard Jenkins

S12 E109: Cuba Gooding Jr., Maksim Chmerkovskiy

S12 E110: Molly Ringwald, Shailene Woodley

S12 E111: Diane Sawyer, Mario Cantone's Grammy recap

S12 E112: Joan Rivers, Daniel Dae Kim

S12 E113: Kate Winslet, Jane Krakowski

S12 E114: Miss Piggy, Patti Stanger, Helen Fisher

S12 E115: Clive Owen, Melissa Leo, AIDS expert Jorge Rodriguez

S12 E116: Patricia Arquette, Emily Osment

S12 E117: Cast members from Broadway's "Shrek the Musical"

S12 E118: Bonnie Hunt, Ben Lyons and Ben Mankiewicz

S12 E119: Laurence Fishburne, Lori Klein

S12 E120: Tyler Perry, Keshia Knight Pulliam

S12 E121: Jane Fonda

S12 E122: Tom Jones

S12 E123: Jeff Foxworthy, Labelle

S12 E124: The co-hosts judge their first-ever "Mutt Dog Show"

S12 E125: Rob Lowe, Jason Mesnick

S12 E126: A day of Hot Topics

S12 E127: Marcia Gay Harden

S12 E128: Dr. Phil McGraw, RuPaul

S12 E129: Glenn Close, Rachel Maddow

S12 E130: Jeffrey Dean Morgan, Nathan Fillion

S12 E131: Miley Cyrus, Jimmy Kimmel

S12 E132: Jay Leno, Carrie Ann Inaba, Bruno Tonioli, Len Goodman, Lady GaGa

S12 E133: Patrick Dempsey, Robert Iger

S12 E134: Kyle MacLachlan, Doug Savant, Maurice Benard

S12 E135: Sally Field, Calista Flockhart, Heidi Montag and Spencer Pratt

S12 E136: Jean Chatzky

S12 E137: Gary Sinise, Dr. Drew Pinsky, Jay Mohr

S12 E138: Taye Diggs, Ian McShane, Valentino

S12 E139: Jaime Pressly, Troy Dunn

S12 E140: Regis Philbin, John Rendall and Ace Bourke

S12 E141: A day of Hot Topics

S12 E142: Kevin Bacon, Spencer Grammer, the Bacon Brothers

S12 E143: Ray Liotta, Kevin McKidd, the Blind Boys of Alabama

S12 E144: Angela Lansbury, Virginia Madsen, Cheryl Hines

S12 E145: Susan Sarandon, Geoffrey Rush, Carol Leifer

S12 E146: Bill O'Reilly, The Dead

S12 E147: Jonathan Rhys Meyers, Alyssa Milano

S12 E148: Lauren Graham

S12 E149: Mary Tyler Moore, Sean Astin, Craig Shoemaker

S12 E150: Bob Saget, Alexandra Wentworth

S12 E151: Zac Efron, style expert Lloyd Boston

S12 E152: How to Get a Job

S12 E153: Tori Spelling, Bobby Flay

S12 E154: Tom Bergeron, Kristin Chenoweth

S12 E155: Matthew Perry, Tracy Pollan

S12 E156: Dr. Steven Lamm

S12 E157: Sally Quinn, Quinn Bradlee, Candy Spelling, Suzy Welch, Lily Allen

S12 E158: Jeremy Irons, the Clark Sisters

S12 E159: Beyonce, Jim Parsons, guest co-host Meghan McCain

S12 E160: Lil Wayne, Jamie Luner, guest co-host Meghan McCain

S12 E161: A day of Hot Topics

S12 E162: Emily Deschanel, Kim Kardashian, Faith Prince

S12 E163: Marlee Matlin, Harold Perrineau

S12 E164: Rick Warren, Ashley Madison CEO Noel Biderman

S12 E165: Jay Mohr, a performance by the Broadway cast of "9 to 5"

S12 E166: James Carville, Paul Potts

S12 E167: Donald Trump, Ivanka Trump, wrestler MVP

S12 E168: Biz Stone, Evan Williams, Judge Judy Sheindlin, Justin Chambers

S12 E169: Michael J. Fox, Dr. Nancy Snyderman

S12 E170: Kenneth Branagh, Leonard Nimoy, Alyse Myers, John Stossel

S12 E171: Steve Harvey, En Vogue

S12 E172: Melina Kanakaredes, Maya Rudolph

S12 E173: Cheryl Saban, Michael Emerson

S12 E174: Brooke Shields, Neal McDonough

S12 E175: Tom Hanks, Ayelet Zurer, Ron Howard

S12 E176: Jesse Ventura

S12 E177: Elizabeth Edwards

S12 E178: Glenn Beck

S12 E179: Larry King, stars of "Southern Belles: Louisville"

S12 E180: Caroline Manzo, Dina Manzo, Jacqueline Laurita, Sharlene Azam

S12 E181: Wounded soldiers Melissa Stockwell and Ireshekia Henry, Soulja Boy Tellem

S12 E182: Faith Prince

S12 E183: Tyler Florence, Dr. Donnica Moore, The Broadway cast of "Next to Normal"

S12 E184: David Hyde Pierce, Justin Long, Mellody Hobson

S12 E185: Nathan Lane, Bill Irwin

S12 E186: Paris Hilton

S12 E187: Edie Falco, Nia Vardalos, the Broadway cast of "West Side Story"

S12 E188: Vanessa Williams, Claire Shipman

S12 E189: Chandra Wilson, Paula Froelich

S12 E190: Neil Patrick Harris, Lionel Richie

S12 E191: Francis Ford Coppola

S12 E192: Mandy Moore

S12 E193: Kanye West, Stephen Moyer

S12 E194: Melissa Gilbert, Joe Scarborough

S12 E195: Black Eyed Peas

S12 E196: Wrestler MVP, Dr. Larry Norton

S12 E197: Jada Pinkett Smith, food stylist Lauren Costello

S12 E198: Michelle Pfeiffer, Rupert Friend, Shirley Jones, Marty Ingels

S12 E199: Lauren Conrad, Anne Hathaway

S12 E200: George Lopez, Mario Cantone, Lewis Black

S12 E201: Nancy Grace

S12 E202: Maksim Chmerkovskiy, Benjamin Bratt, Warren Boyd

S12 E203: Joan Rivers, designer Michael Smith

S12 E204: Larry David, Evan Rachel Wood, Darius Rucker

S12 E205: John Edward

S12 E206: Larry Miller

S12 E207: Denis Leary, Rob Thomas

S12 E208: Teri Hatcher, beauty expert Marie Czenko Kuechel

S12 E209: Margaret Cho, LL Cool J

S12 E210: Minnie Driver, Tyler Florence

S12 E211: A day of Hot Topics

S12 E212: Jimmy Fallon, Kevin Connolly

S12 E213: Steve Harvey, Daughtry

S12 E214: Thomas Jane, Jane Adams, Bill Engvall, Dr. Donnica Moore

S12 E215: Jeff Daniels, Lauren Graham, Tyler Florence

S12 E216: Charles Gibson

S12 E217: David Hasselhoff, the Script

S12 E218: Tyler Florence

S12 E219: Demi Lovato, Miss USA 2009 Kristen Dalton

S12 E220: Kevin Spacey

S12 E221: Mary Jo Buttafuoco

S12 E222: Jessica Lange, Dr. Gadget

S12 E223: Ashley Tisdale, Hugh Dancy, Rose Byrne, Dr. Timothy Johnson

S12 E224: Seth Rogen, Judd Apatow

S12 E225: Constantine Maroulis, Tyler Florence

S12 E226: Michelle Malkin

S12 E227: Eric Bana

S12 E228: James Brolin, Selena Gomez, David Henrie, Jake T. Austin, the Broadway cast of "Hair"

S12 E229: Regis Philbin

S12 E230: Meryl Streep, Amy Adams, Nora Ephron, Lauren Costello

S12 E1103: George Stephanopoulos, Seth Meyers

S12 E1104: Dennis.Hopper

S12 E1111: Elton John

S12 E1112: Alicia.Keys

S12 E1113: John.Stamos

S12 E1114: Rachael Ray

S12 E1117: Hot Topics

S12 E1118: Jessica Lange

S12 E1124: Simon Baker

S12 E1125: Faith Hill

S12 E1126: Teri Hatcher

S12 E1128: Nicole Kidman

S12 E1201: Randy Jackson

S12 E1202: Patricia Heaton

S12 E1203: Jeff Goldblum

S12 E1204: Harry Connick, Jr

S12 E1205: Hugh Jackman

S12 E1208: Paula Abdul

S12 E1209: Don Rickles

S12 E1210: Day of Hot Topics

S12 E1211: Dr. Mehmet Oz

S12 E1212: Meryl Streep

S12 E1215: Keri Russell

S12 E1216: Samuel L. Jackson

S12 E1217: Hot Topics

S12 E1218: Michael Bloomberg

S12 E1222: Comedy Theme Show