S4 E1: Al Sharpton, Kenny Mayne

S4 E2: Carmen Electra, Autolux

S4 E3: John Mayer Trio

S4 E4: Cheryl Hines, David Banner

S4 E5: Dominic Monaghan, Lil' Wayne

S4 E6: Quentin Tarantino, Tia Carrere, John Daly

S4 E7: David Boreanaz, Henry Phillips

S4 E8: Evangeline Lilly, Jonathan Rhys-Meyers, Giant Drag

S4 E9: John Mayer Trio, Steve-O

S4 E10: Michael Chiklis, Roselyn Sanchez, Bo Bice

S4 E11: Adewale Akinnuoye-Agbaje, Drew Lachey, Chamillionaire ft. Lil' Flip

S4 E12: Method Man, Motion City Soundtrack, Jerry Bruckheimer

S4 E13: David Gest, Feist

S4 E14: Regis Philbin, Jordana Brewster, She Wants Revenge

S4 E15: Jerry Rice, Mike Epps, Mike O'Connell

S4 E16: Martin Lawrence, Dem Franchize Boyz ft. Bow Wow, Jermaine Dupri

S4 E17: Kid Rock, David Alan Grier

S4 E18: David Spade, Rob Schneider, Jon Heder, Dwele

S4 E19: Michael Irvin, Jeff Daniels, The Four Tops, Buddy Guy

S4 E20: Jessica Alba, Anthony Anderson, The Four Tops

S4 E21: SuperBowl Episode

S4 E22: Mischa Barton, Travis Barker & Shanna Moakler, James Blunt

S4 E23: Jorge Garcia, Dan Naturman, Nelly

S4 E24: Wilmer Valderrama, Dan Naturman, Golden Brooks, Dwight Yoakam

S4 E25: Nick Cannon, Kathy Griffin, Damian Marley

S4 E26: Steve Coogan, Travis Stork, Daddy Yankee

S4 E27: Freddie Prinze, Jr., John Daly, Jacks Mannequin

S4 E28: Flavor Flav

S4 E29: Fred Savage, Harold Perrineau Jr., Yellowcard

S4 E30: Jack Osbourne, Carolyn Murphy, Dem Franchize Boyz

S4 E31: Shaun White, Steve Harvey, Hawthorne Heights

S4 E32: Kathie Lee Gifford, Yehya Mohamed, Augustana

S4 E33: Simon Cowell, Jennifer Esposito, Dilated Peoples

S4 E34: Cuba Gooding Jr., Mike Birbiglia

S4 E35: Paul Walker, Hannah Teter, Bow Wow, Travis Barker

S4 E36: Kelly Ripa, Tracy Morgan

S4 E37: Stacy Keibler, Howie Mandel, Three Six Mafia

S4 E38: Jamie Oliver, Sasha Cohen, OK Go

S4 E39: After the Academy Awards

S4 E40: Zooey Deschanel, Dave Sheridan, Panic! At the Disco

S4 E41: Amanda Bynes, Chuck Lidell, Jamie Cullum

S4 E42: Michael Rapaport, Elisha Cuthbert, Matisyahu

S4 E43: John Lydon, Orlando Jones, Jim Gaffigan

S4 E44: Ice Cube, Elantu B. Veovode, Nine Black Alps

S4 E45: Adam Brody, John Cena, Juvenile featuring Galactic

S4 E46: Randy Jackson, Janet Reno, Hard-Fi

S4 E47: James Caan, Justin Chambers, The Tossers

S4 E48: Hulk Hogan, Yunjin Kim, Harold & Darrell Allen

S4 E49: George Lopez, Duane "Dog" Chapman, the Sounds

S4 E50: Jamie-Lynn Sigler, Larry the Cable Guy, Gogol Bordello

S4 E51: Kiefer Sutherland, Rocco DeLuca

S4 E52: Seth Green, Chop from "King of Cars," Anthony Jeselnik, John Anderson

S4 E53: Anthony Anderson, Pete Rose

S4 E54: Carmen Electra, David Gest, People in Planes

S4 E55: Tori Spelling, C. Thomas Howell, T.I.

S4 E56: Rebecca Romijn, Judge Marilyn Milian, T-Pain

S4 E57: Chris Matthews, Craig Bierko

S4 E58: Wilmer Valderamma, Chris Elliott, The Wiggles

S4 E59: Charlie Sheen, Rube Goldberg Contest winners, K.T. Tunstall

S4 E60: Paula Abdul, Enrico Colantoni, Mighty Gonzalez

S4 E61: Cheryl Hines, Landon Donovan, Bril

S4 E62: Eva Longoria, Dick Cavett, Dresden Dolls

S4 E63: Regis Philbin, Barry Watson, Mike Birbiglia

S4 E64: Natasha Henstridge, Robert Wuhl, the cast of MTV's "Call to Greatness"

S4 E65: LL Cool J, Robert Klein

S4 E66: Guy Pearce, Ludacris, Atmosphere

S4 E67: Susan Lucci, Adam Carolla, Rihanna

S4 E68: Joe Gannascoli, Kellie Pickler, Adam Carolla, Godsmack

S4 E69: Jenny McCarthy, Seth MacFarlane, The Cult

S4 E70: Sir Ian McKellen, Jared Leto, Franz Ferdinand

S4 E71: Chris O'Donnell, American Chopper Guys

S4 E72: Kathie Lee Gifford, Isaiah Washington, Art Brut

S4 E73: Famke Janssen, Jared Leto, 30 Seconds to Mars

S4 E74: Carl Reiner, Ashley Tisdale, Ivan Kane's Royal Jelly dancers, Martin Fry

S4 E75: Reggie Bush, Pat O'Brien, Lacuna Coil

S4 E76: Jamie Kennedy, Daryl Hannah, Jonathan Rice

S4 E77: Rev. Jesse Jackson, Jimmy Bennett, Nick Lachey

S4 E78: Dominic Monaghan, J.J. Abrams, Taking Back Sunday

S4 E79: Katherine Heigl, James Pickens Jr., Chandra Wilson, Ben Lee

S4 E80: Drew Carey, Malcolm David Kelley, Christina Milian

S4 E81: Teri Hatcher, Umphrey's McGee featuring Huey Lewis

S4 E82: Sarah Silverman, Artie Lange, Hoobastank

S4 E83: Sarah Silverman, James Cramer, Denny "Average Homeboy" Blaze

S4 E84: Julia Stiles, Jason Ritter, Atreyu

S4 E85: Jon Favreau, Mike Iaconelli, Elefant

S4 E86: Dane Cook, Brett Ratner

S4 E87: Ice Cube, Paget Brewster

S4 E88: Jessica Alba, Larry the Cable Guy, Him

S4 E89: Rosie Perez, Jared Hess, Elefant

S4 E90: John C. Reilly, Gary Gulman

S4 E91: Jaime Pressly, Xzibit, The Streets

S4 E92: Luke Perry, Jean Smart, Huey Lewis

S4 E93: Jack Black, Wolfmother

S4 E94: Fiona Apple

S4 E95: Ozzy Osbourne, Anthony Bourdain

S4 E96: Bonnie Hunt, Phil Gordon, Buckcherry

S4 E97: Geena Davis, Louis C.K., Jeff Corwin

S4 E98: Mariah Carey, Rob Zombie

S4 E99: Jason Alexander, Meagan Good, Jamie Kennedy

S4 E100: Tommy Lee, 98-year-old high school student Josephine Belasco, Greg Fitzsimmons, the Fixx

S4 E101: George Foreman, psychotherapist Richard Cohen, Blue October

S4 E102: Kathy Griffin, Jason Gray-Stanford, the Brand New Heavies

S4 E103: Ed Burns, NBA Finals MVP Dwayne Wade, Flyleaf

S4 E104: Tracy Morgan, Shaun Alexander, Sonic Youth

S4 E105: Lance Armstrong, Matt Dallas, Smoosh

S4 E106: Brittany Murphy, Danica Patrick, Eagles of Death Metal

S4 E107: Terrell Owens, Rainn Wilson, Rascal Flatts

S4 E108: Shawn & Marlon Wayans, Fred Willard, Korn

S4 E109: Robin Williams, Anna Faris, Rhymefest

S4 E110: Allison Janney, Morgan Spurlock, Jurassic 5

S4 E111: Rosario Dawson, Jesse Metcalf, the Flaming Lips

S4 E112: Gene Simmons, Jeff Ross, the Elected

S4 E113: Jon Cryer, the Dudesons, Los Lonely Boys

S4 E114: Regis Philbin, Trevor Fehrman, Pharrell

S4 E115: Flavor Flav, Leslie Bibb, Ben Harper

S4 E116: Sandra Oh, Jewel

S4 E117: Cheryl Hines, Shaun White, Russell Peters

S4 E118: Will Ferrell, Bobby Cannavale, Under the Influence of Giants

S4 E119: Matt Dillon, Justin Long, Ziggy Marley

S4 E120: Jonathan Winters, Kenan Thompson, Against Me!

S4 E121: Paul Reubens, snake handler Jules Sylvester, Obie Trice, Leonid "the Magnificent" Filatov

S4 E122: Samuel L. Jackson, Elisha Cuthbert, Cobra Starship

S4 E123: Heidi Klum, Dave Navarro, Panic Channel

S4 E124: Hillary Duff, Ultimate Fighting Champion Chuck Lidell, Anti-Flag

S4 E125: Tom Cavanaugh, Tommy Chong, Cartel

S4 E126: Anthony Michael Hall, Joan & Melissa Rivers, the Red Jumpsuit Apparatus

S4 E127: Kevin Nealon, Jay Chandrasekhar, Pat Green

S4 E128: Tommy Lee, Wayne Brady, Starsailor

S4 E129: Michael Rapaport, Jimmie Johnson, Jo Koy, Wayman Tisdale

S4 E130: Lauren Holly, private investigator Vinny Parco, the Roots

S4 E131: Ron Livingston, Toby Keith

S4 E132: Anthony Michael Hall, James Carville, Robert Randolph and the Family Band

S4 E133: Tyra Banks, Jason Statham, Papa Roach

S4 E134: Orlando Bloom, Emily Deschanel, Lyfe Jennings

S4 E135: Diane Lane, celebrity photographer Yehya Mohamed, Chingy

S4 E136: Chris Elliott, Rachel Bilson, LeToya

S4 E137: Sarah Silverman, Lionel Richie

S4 E138: Zach Braff, Xzibit, Josh Radin

S4 E139: Dwayne "The Rock" Johnson, Bam Margera, Lupe Fiasco

S4 E140: Felicity Huffman, Jet Li, Human League

S4 E141: Johnny Knoxville, Kim Raver, Patrizio

S4 E142: George Lopez, Clay Aiken

S4 E143: Jon Heder, Don, Mole and Perry, The Red Jumpsuit Apparatus

S4 E144: Evangeline Lilly, Anthony Anderson, Ludacris

S4 E145: Eva Longoria, Artie Lange

S4 E146: Dax Shepard, Jordana Brewster, The Killers

S4 E147: Dane Cook, Emilie de Ravin, The Killers

S4 E148: Jessica Simpson, Carlos Mencia, The Killers

S4 E149: Andy Dick, Diora Baird, Jet

S4 E150: Jason Lee, America Ferrera, Gym Class Heroes

S4 E151: Wanda Sykes, Sun Ming Ming, Ruben Studdard

S4 E152: Robin Williams, Rod Stewart

S4 E153: Justin Timberlake, Kate Walsh

S4 E154: John Stamos, Bobcat Goldthwait, Ivan Kane's Royal Jelly

S4 E155: Anne Heche

S4 E156: Ted Danson, Jennifer Tilly, Xzibit

S4 E157: Terry Bradshaw, Matt Davis, Lloyd Banks

S4 E158: Kathy Griffin, Shawnee Smith, Meat Loaf

S4 E159: Sharon Osbourne, Josh Radnor, the Wreckers

S4 E160: Roseanne Barr, Joseph Cross

S4 E161: Val Kilmer, Bowling for Soup

S4 E162: Lauren Graham, Ricardo Chavira, Anita Baker

S4 E163: Diddy, Tony Hawk

S4 E164: Julia Louis-Dreyfus, Lady Sovereign

S4 E165: Don Rickles, Nick and Aaron Carter, The Hold Steady

S4 E166: Pamela Anderson, Geraldo Rivera, Brent Simon

S4 E167: Tracy Morgan, Jerry Springer, Akon

S4 E168: Brittany Murphy, Shia LaBeouf, John Legend

S4 E169: Greg Kinnear, Marla Sokoloff, Sherrod Small

S4 E170: Billy Crystal, Ricky Martin

S4 E171: Teri Hatcher, Gary Brolsma, Rock Star Supernova

S4 E172: Regis Philbin, Jay-Z

S4 E173: Wilmer Valderrama, Michael Irvin, Chris Daughtry

S4 E174: Taye Diggs, Teri Garr, Todd Glass

S4 E175: Rachel Weisz, Chi McBride, Jenny Lewis

S4 E176: Elijah Wood, Tichina Arnold, Mute Math

S4 E177: David Allen Grier, Tatum O'Neal, Lily Allen

S4 E178: Thandie Newton, Peter Falk, Bow Wow with Chris Brown

S4 E179: Tom Arnold, Jo Frost, Corinne Bailey Rae

S4 E180: Ted Danson, Mary J. Blige

S4 E181: Jessica Biel, Mario Batali, Fantasia

S4 E182: Shawn and Marlon Wayans, Eric Dane, The Living End

S4 E183: Ryan Seacrest, Beck

S4 E184: Howard Stern, Forest Whitaker, Nas

S4 E185: Matthew Fox, Lawrence Taylor, +44

S4 E186: Adam Carolla, Giovanni Ribisi, OK Go

S4 E187: Sylvester Stallone, Gnarls Barkley

S4 E188: Matthew McConaughey, Yao Ming, Tracy McGrady, Hall & Oates

S4 E189: George Lopez, Giuliana DePandi, My Chemical Romance